Occupational Safety and Health (OSH) is an area concerned with protecting the safety, health and welfare of people engaged in work or employment. The goals of occupational safety and health programs include fostering a safe and healthy work environment. The National Institute for Occupational Safety and Health (NIOSH) is the U.S. Federal Agency for the prevention of Workplace Illnesses and Injuries.
The aim of this work is the screening of the volatile compounds according to the NIOSH 2549 method from NMAM (NIOSH Manual of Analytical Methods). This study was conducted using a system composed by two stage thermal desorber - gas chromatograph – time of flight mass spectrometer (TD- GC/TOF MS).
The analytical performance has been investigated.
At first, a certain volume of sample is concentrated in a sorbent tube. This tube is heated and the volatile compounds are then desorbed by a flow of inert gas and transferred to a narrow-bore packed trap filled with one or more sorbent materials, and concentrated at low temperature. Once the refocusing step is completed, the trap is instantaneously heated providing a rapid analytes transfer directly into the GC/TOF MS system. Ther¬mal desorption and gas chromatographic analysis is a suitable approach to perform an accu¬rate and cost-effective monitoring. Data will be reported including chromatographic parameters for VOC and qualitative determinations.