Organophosphorus Pesticides are among the most widely used class of pesticides thanks to their high efficacy against pests. They are also well known for their poisoning effects on human health as the over-exposure to organophosphorus pesticides may cause irreversible damage to the nervous system and have neurotoxic effects on developing organisms. They can be, in fact, absorbed by inhalation, ingestion, and dermal absorption.

These compounds represent a concrete risk for the environment, also. Industrial waste, seepage from buried toxic wastes, and contamination during spraying operations, they all can be considered as possible ways for their introduction into the water.

EPA Method 622 is a gaschromatographic (GC) method appliable to the determination of certain organophosphorus pesticides in industrial and municipal discharges as provided under 40 CFR 136.1.

The analysis below is an example, applicable to complex mixtures, that shows how to reach the method detection limits. These outstanding results can be achieved thanks to an increased peak resolution and the use of a particularly selective and sensitive detector.

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